My guest this episode is Dr. Peter Attia, M.D., who trained at Stanford University School of Medicine, Johns Hopkins Hospital and the National Institutes of Health (NIH). Dr. Attia is host of The Drive podcast and is a world expert on behavioral approaches, nutritional interventions, supplementation and pharmacological techniques to improve lifespan, healthspan and athletic performance. We discuss how best to evaluate your health status using routine blood work, body scans and regular tests of physical strength and endurance. Dr. Attia explains what he uses with his patients to “back-cast” their health goals as a way to design their exercise and nutritional programs. We also discuss hormone modulation and replacement therapy for both men and women. We explain how cholesterol and related factors contribute to cardiovascular disease risk and how to monitor and mitigate that risk. Dr. Attia details various supplementation, nutrition, exercise and prescription approaches useful to people in every decade of life to improve vitality, reduce their risk of disease and increase the number of years sustaining peak cognitive and physical health.
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Timestamps
00:00:00 Assessing Health Status & Improving Vitality
00:02:51 Momentous Supplements
00:03:46 Thesis, InsideTracker, Helix Sleep
00:07:29 Lifespan: Bloodwork & Biomarkers Testing, The “4 Horseman of Disease”
00:11:51 Healthspan: Functional Testing, Cognitive & Emotional States
00:13:59 Blood Testing: Best Frequency
00:16:01 DEXA Scan: Lean Mass & Fat, Bone Mineral Density & Osteoporosis
00:22:33 Bone Mineral Density & Age-Related Decline, Strength Training, Corticosteroids
00:29:24 Osteopenia & Osteoporosis Diagnosis, Strength Training
00:31:03 AG1 (Athletic Greens)
00:32:16 Back-casting: Defining Your “Marginal Decade”
00:38:31 All-Cause Mortality: Smoking, Strength, VO2 max
00:44:43 Attia’s Rule of Supplementation, “Centenarian Decathlete” Physical Goals
00:49:24 Importance of Exercise, Brain Health, MET hours
00:55:23 Nicotine & Cognitive Focus
01:03:12 Menstruation, PMS & Menopause
01:10:10 Hormone Replacement Therapy, Menopause & Breast Cancer Risk
01:22:06 Estrogen, Progesterone & Testosterone Therapies in Women
01:26:35 Hormone Replacement Therapy in Men, SHBG & Testosterone, Insulin
01:37:23 Clomid, Pituitary, Testosterone & Cholesterol, Anastrozole, HCG
01:47:46 Fadogia Agrestis, Supplements, Rapamycin
01:52:06 Testosterone Replacement Therapy & Fertility
01:59:26 Total Testosterone vs. Free Testosterone
02:02:51 Cholesterol & Dietary Cholesterol, Saturated Fat, LDL & HDL, Apolipoprotein B
02:17:42 Apolipoprotein B, Diet, Statins & Other Cholesterol Prescriptions
02:25:15 Cardiovascular Disease, Age & Disease Risk
02:28:53 Peptides, Stem Cells, BPC157, PRP (Platelet-Rich Plasma), Injury Rehabilitation
02:37:40 Metabolomics & Exercise
02:40:44 GLP-1 & Weight Loss
02:47:06 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips
#HubermanLab #PeterAttia #Longevity
Title Card Photo Credit: Mike Blabac –
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